If you monitor with fingerstick testing, add a bedtime check to your usual morning and pre-meal schedule
It is postulated that GLP-1 RAs activate the GLP-1 R and transactivate the epidermal growth factor receptor (EGFR) via metalloproteinases
Disruption of this process, known as ER stress, is associated with many disease states, including obesity and its comorbidities (Mohan, R, Brown, Ayyappan, & G, 2019)
Newer compounds like retatrutide add a third receptor target (GIP, GLP-1, and glucagon) and may create unique nutritional challenges that have not yet been well-studied
Your workout doesnt need to be extremeit just needs to be consistent